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GSK reports promising early results in ovarian and womb cancer drug trial

Mo-Rez reduced or eliminated tumours in over 60% of patients and is expected to be a blockbuster drug GSK has revealed positive results for a treatment for gynaecological cancers as its chief executive, Luke Miels, steps up drug development efforts at the group. The company said that in an early-stage trial Mocertatug Rezetecan, known as Mo-Rez, shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer. Continue

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Richard Tice’s firm alleged to have broken law by failing to pay tax

Report says company did not pay tens of thousands in tax on dividends given to Reform UK deputy leader and trust Richard Tice’s company has been accused of breaking the law by allegedly failing to pay tens of thousands of pounds in tax on dividends that were paid to him and his offshore trust. Reform UK’s multimillionaire deputy leader is alleged to have received at least £91,000 in excess payments as a result, the Sunday Times reported . Dan Neidle of Tax Policy Associates – whose analysis was

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What's next in reaching the moon after Artemis II

What's next in reaching the moon after Artemis II

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Ex-CIA director calls for ousting Trump: ‘25th amendment was written with him in mind’

John Brennan says president who made volatile remarks about destroying Iranian civilization ‘is clearly unhinged’ The former Central Intelligence Agency director John Brennan has added his name to growing calls for the president to be ousted on grounds that he is unfit for the job, arguing that the US constitution’s 25th amendment addressing involuntary removal from office was “written with Donald Trump in mind”. Brennan, who served as head of the spy agency during Barack Obama’s presidency, tol

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Anthony Albanese urges Israel to stop Lebanon attacks that intensified during Middle East ceasefire

PM tells Guardian Australia Hezbollah should cease reprisals and confirms Australia’s military surveillance aircraft will remain in region Get our breaking news email , free app or daily news podcast Australia’s prime minister, Anthony Albanese, has urged Israel to stop its attacks on Lebanon and raised concern over its intensified military campaign on Beirut and the country’s south after the ceasefire in the Middle East. Albanese also called on Hezbollah to cease attacks on Israel, reiterating

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Australia should set immigration targets to achieve a ‘stable temporary population’, report says

Experts say our preoccupation with net overseas migration figures has distracted from a more meaningful discussion on the ‘scale of temporariness’ Get our breaking news email , free app or daily news podcast Australia should set immigration targets to achieve a “stable temporary population” to address the ballooning number of nonpermanent residents that has stretched the country’s public services and housing, a new report argues. Temporary migrants as a share of the total population has more tha

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NBC News · Oct 8

Pramila Jayapal says she will vote to expel Swalwell, Gonzales: ‘This is not a partisan issue’

Rep. Pramila Jayapal (D-Wash.) tells Meet the Press she will vote to expel Rep. Eric Swalwell (D-Calif.) and Rep. Tony Gonzales (R-Texas), saying she “is inspired by the courage and the bravery of the women” who stepped forward with sexual misconduct allegations against the two congressmen.

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Guardian - World · Oct 8

Planeloads of negotiators and too little time: US and Iran’s 21 hours of talks

Two sides tested one another’s resolve but timeframe meant it was probably unrealistic to expect deal Middle East crisis – live updates It was if the two delegations in the Iran-US peace talks in Islamabad hoped that the sheer number of negotiators flown into Pakistan could overcome the handicap of having only a finite number of hours in which to settle a 20-year dispute over Iran’s nuclear ambitions, now overlaid by complex new issues such as future control of the strait of Hormuz and US compen

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NBC News · Oct 8

After collapse of U.S.-Iran talks in Pakistan, the path to peace is less clear

A vendor pushes his cart past a giant billboard reading 'The Strait of Hormuz remains closed' at the Revolution Square in Tehran on April 12.

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NBC News · Oct 8

U.S.-Iran talks: Where relations stand after no deal

U.S.-Iran talks: Where relations stand after no deal

Today's highlights

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Cuban president says ‘if we need to die, we’ll die’ to prevent U.S. invasion: Full interview

In his first-ever interview on American television, Cuban President Miguel Díaz-Canel tells Meet the Press that Cuba would fight back against any potential U.S. military action, saying Cuban leadership is prepared to “give our lives for the revolution.”

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US and Iran Fail to Reach Peace Deal: What It Means for the War

Meet the Press Moderator Kristen Welker joins Sunday TODAY’s Willie Geist to discuss what comes next after the United States and Iran failed to reach a peace deal amid the fragile ceasefire agreement.

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Peruvians go to the polls hoping to break cycle of instability

Soaring crime and corruption top voter concerns in highly unpredictable election with record 35 candidates for president Peruvians go to the polls on Sunday hoping to break a cycle of instability that has produced nine presidents in a decade as well as surging violent crime , corruption scandals and overwhelming distrust in institutions and politicians. About 27 million people who are eligible to vote must choose between a record 35 presidential candidates as well as contenders for a bicameral c

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‘I didn’t want to be on medication the rest of my life’: veteran runs psilocybin retreats for PTSD before FDA approval

Researchers say ‘magic mushrooms’ can help with traumatic symptoms, but urge caution as states expand access Sign up for the Breaking News US email to get newsletter alerts in your inbox After three combat deployments in Afghanistan, during which he suffered traumatic brain injuries from concussive blasts, army ranger Jesse Gould developed post-traumatic stress disorder and said he “drank almost every night to cope”. In times of hardship, veterans sometimes turn to “medication and talk therapy,

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NBC News · Oct 8

Cuban president: 'We would die' to defend against U.S. invasion

In his first-ever interview on American television, Cuban President Miguel Díaz-Canel tells Meet the Press that Cuba would fight back against any potential U.S. military action, saying Cuban leadership is prepared to “give our lives for the revolution.”

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Guardian - World · Oct 8

Collapse of US-Iran talks heightens fears of prolonged energy shock

Oil prices and borrowing costs are expected to rise this week as tankers remain stranded in Persian gulf Middle East crisis live – latest updates The failure of the US and Iran to reach a peace deal after marathon negotiations has put markets on alert for further oil and gas price rises. With large numbers of oil tankers remaining stuck in the Persian gulf, the US vice-president, JD Vance blamed the collapse of the talks on Tehran’s refusal to abandon its nuclear weapons programme, while Iranian

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NBC News · Oct 8

Cuba's president says 'we would die' to defend against U.S. invasion

NBC News' "Meet the Press" moderator Kristen Welker and Cuban President Miguel Díaz-Canel.

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Blue city, red state battle: Kansas City feuds over ‘colonial’ police system

Democratic city does not control its police force – and reform attempts have been thwarted by Republicans Quinton Lucas said he thinks his city’s police department “is a colonial system”. “I think it is anti-Black. I think it is anti-immigrant. I think it is anti-almost everything we stand for in terms of making sure that diverse populations in major cities have a voice in terms of navigating it,” the Kansas City mayor said. Continue reading...

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‘Never been closer’: UFO watchers buoyed by Trump and Vance’s alien ‘obsession’

From Vance’s interest to Trump’s commitment to disclosure, administration’s fascination with UFOs has experts feeling close to evidence of aliens Like most politicians, Donald Trump did not campaign on the issue of space aliens. But 15 months into his second term, UFO enthusiasts have been buoyed by the Trump administration’s apparent fascination with extraterrestrials, with one expert claiming the human race has “never been closer” to being presented with hard evidence of aliens. After a largel

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Deal of the Day: Get almost 60% off these popular vacuum storage bags

To compress these vacuum storage bags, just attach the hose of your vacuum.