Popular weight-loss drugs linked to unexpected male fertility benefit

Taking a GLP-1 medication for weight loss may improve male fertility, according to experts. Research presented this week at ENDO 2026, the Endocrine Society’s annual meeting in Chicago, explored how obesity is strongly linked to fertility problems in men. Excess weight can contribute to dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis — the hormone system that regulates testosterone production — and functional hypogonadism, a condition in which testosterone levels are abnormally lo